| Place of Origin: | China |
|---|---|
| Brand Name: | Mitejian |
| Certification: | COA MSDS |
| Model Number: | CAS 1421373-66-1 |
| Minimum Order Quantity: | 1g |
| Price: | $10~20/g |
| Packaging Details: | Sealed tin foil bags, barrels, cartons |
| Delivery Time: | 10~14 work days |
| Payment Terms: | L/C, T/T, Western Union, MoneyGram,Bitcoin ,ETH ,USDT... |
| Supply Ability: | 100000kg/month |
| English Name: | AZD-9291 Mesylate | Apperance: | Powder |
|---|---|---|---|
| Density: | N/A | Molecular Formular: | C29H37N7O5S |
| Molecular Weight: | 595.713 | Boiling Point: | N/A |
| Melting Point(oC): | N/A | Flash Point: | N/A |
| Exact Mass: | 595.257690 | ||
| Highlight: | 1421373-66-1 Azd9291 Mesylate,Azd9291 Mesylate White Powder,MSDS Azd9291 Mesylate |
||
High purity with Good Price White powder AZD-9291 Mesylate CAS 1421373-66-1
| CAS No. : | 1421373-66-1 |
| English Name : | AZD-9291 Mesylate |
| English Alias : | Osimertinib mesylate |
| Density : | N/A |
| Boiling Point : | N/A |
| Melting Point(oC) : | N/A |
| Molecular Formular : | C29H37N7O5S |
| Molecular Weight : | 595.713 |
| Flash Point: | N/A |
| Exact Mass : | 595.257690 |
| PSA: | 153.79000 |
| LogP: | 5.81710 |
| Vapor pressure: | N/A |
| Refractive index: | N/A |
| HS Code : | N/A |
High purity with Good price AZD-9291 Mesylate CAS 1421373-66-1
Medical use
Osimertinib is used to treat locally advanced or metastatic non-small-cell lung cancer (NSCLC), if the cancer cells are positive for the T790M mutation in the gene coding for EGFR. The T790M mutation may be de novo or acquired following first-line treatment with other tyrosine kinase inhibitors (TKIs), such as gefitinib and afatinib.
In the USA, T790M status of the patient prior to treatment with osimertinib must be detected by a federally approved companion diagnostic test. The F has approved FoundationOne CDx for this purpose. In Europe and elsewhere, T790M mutations may be determined by a validated and suitably sensitive next-generation sequencing assay.
In people treated with osimertinib, resistance usually develops within approximately 10 months. Resistance mediated by an exon 20 C797S mutation accounts for the majority of resistance cases.
It causes fetal harm, so should not be used in women who are pregnant, and women who take it should avoid becoming pregnant.
Caution should be taken in people with a history of interstitial lung disease (ILD) were excluded from clinical trials, as the drug can cause severe ILD or pneumonia. Caution should also be taken in people with a predisposition to long QT syndrome as the drug can provoke this.
RFQ :
1. Can i get some samples?
Yes, we can supply free sample, but please bear shippping cost at your side.
Ship fee will be deducted from future bulk order .
2. How to start orders or make payments?
Proforma invoice will be sent first after confirmation of order, enclosed our
account information.
Payment by T/T, Western Union ,Money Gram ,BTC ,USDT ,ETH .
3. How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping
cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture
the products according to your requests.
4. How long is lead time?
We deliver goods within 1-2 weeks for small order, 2-3 weeks for bulk order.
5: What's your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition
that sample charge is 100% paid.
6. How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero.
If there is a real quality problem caused by us, we will send you free goods
for replacement or refund your loss
